Gadolinium (III) containing MRI contrast agents (often termed simply gado or gad) are the most commonly used for enhancement of vessels in MR angiography or for brain tumor enhancement associated with the degradation of the blood–brain barrier. For large vessels such as the aorta and its branches, the gadolinium …
MRI contrast agent – Wikipedia, Gadolinium Enhancement – Questions and Answers in MRI, Gadolinium Enhancement – Questions and Answers in MRI, Quantitative analysis of whole- tumor Gd enhancement histograms predicts malignant transformation in low-grade gliomas, Gadolinium(III) containing MRI contrast agents (often termed simply gado or gad) are the most commonly used for enhancement of vessels in MR angiography or for brain tumor enhancement associated with the degradation of the blood–brain barrier.
The contrast enhancement produced by intravenous administration of 0.1 mmol/kg of gadolinium-DTPA in these tumors was measured on T1 MR images. Acoustic neuromas showed the greatest enhancement (average, 310%), meningiomas the next greatest (average, 180%), and neurofibromas, glomus tumors , and pituitary microadenomas the least enhancement .
After administration of Gd-DTPA (0.2 or 0.5 mmol/kg), tumor ring enhancement was consistently observed, with patchy, inhomogeneous enhancement within the larger tumors. These obvious enhancement, 25 minutes after injection of Gd-DTPA were significant at both doses for the strongly enhancing areas (P < 0.05 for 0.2 mmol/kg and P < 0.OOi for 0.5 mmol/kg).
